Skip to product information
1 of 8

America’s Most Followed Pet Wellness Brand

4.8
Rated 4.8 out of 5 stars
596 Reviews

250mg CBD Oil | Calm + Comfort - for Pets

250mg CBD Oil | Calm + Comfort - for Pets

When you subscribe, you get:
$155+ Value

Free Bonus Product (while supplies last)

Currently: Exclusive Lillie&Lee Collapsible Bowl

$20 Value

Wellness Toolkit + Wild & Clean Cook Book

Wellness Toolkit for better health & wellness. Plus our Wild & Clean cook book with 42+ recipes.

$35 Value

Pack Loyalty Membership

Exclusive perks, early access & member-only offers

$100+ Value
PLUS SUBSCRIBER SAVINGS
Save 30% on your first order
30% discounted shipping on every order

ATTENTION: NEW CBD LAW RESTRICTIONS

250mg CBD Oil | Calm + Comfort - for Pets

If you are shipping to any of these states please purchase our organic CBD Isolate Oil here:

CA, GA, HI, KS, LA, SD, VA, & MS

Purchase CBD Isolate >
Quantity
  • 90 Day Money Back Guarantee
  • Free Shipping On Order $125+

CA Residents:

IMPORTANT: We are no longer able to ship full spectrum CBD to CALIFORNIA as of July 1st. (CA Law SB 378)

⚠️ WARNING: Cancer and Reproductive Harm – www.P65Warnings.ca.gov

Product Description

Our 250mg CBD Oil delivers a full‐spectrum botanically derived cannabidiol formula that promotes relaxation, supports joint comfort, and encourages restful sleep.

Ingredients

  • 100% Full Spectrum CBD Oil
  • MCT Oil (for optimal absorption)

Potency: 250mg per 1 oz bottle

Problem?

Is stress, restlessness, or occasional aches slowing your pet down?

What It Is

  • Full‐Spectrum CBD Extract: Advanced, botanical extraction containing CBD along with naturally occurring minor cannabinoids and terpenes.
  • Two-Ingredients: Formulated for pets, with only CBD and flavor‐neutral CT carrier oil to suit every palate.
  • Consistent Strength: Each drop contains a reliable, measured amount of CBD to ensure effortless, accurate administration.

Why It Works

  • Stress Support: CBD interacts with the body’s endocannabinoid receptors to help calm overactive stress responses.
  • Joint & Muscle Relief: Naturally soothes discomfort by modulating inflammatory pathways, aiding mobility and ease of movement.
  • Sleep & Recovery: Encourages deeper, more restorative sleep cycles by balancing neurotransmitters involved in rest regulation.
  • Holistic Balance: Supports overall endocannabinoid system health, enhancing emotional resilience and physical well-being across species.

How to Use

Our 250mg CBD is best for pets under 40lbs.

Administer orally 1-2 times daily. Can be given during or after mealtime. For optimal benefits, we recommend daily use. Dosage dependent on weight:

Recommended use:

Pets 1–24 lbs: 1/2 dropper (~4 mg)

Pets 25–50 lbs: Full dropper (~8 mg)

  • Premium Quality
  • No Junk Ever!
  • Pet-Parent Trusted
  • Community You Love
View full details

Why Dogs Loves It

Pure Ingredients, Zero Compromise.

No fillers, ever. Just full spectrum CBD in its most natural form — because your dog deserves nothing but the best.

Calm When It Counts

Fireworks, car rides, vet visits — life can be stressful for pups. Our CBD oil helps them stay cool, relaxed, and happy no matter what's happening around them.

Wake Up Wagging

Great days start with great sleep. Our CBD oil helps your pup get the deep, restorative rest they need to feel their absolute best.

Move More, Hurt Less

Our formula supports better mobility and healthier joints so they can keep up with the fun.

Tested. Verified. Transparent.

Meet the cannabinoids working for your pet.

Every Lillie & Lee CBD product is third-party tested for purity, potency, and safety - because your pet's wellness deserves nothing less than certainty. Download our Certificate of Analysis and see exactly what's inside.

Certificate of Analysis

Download COA

CBC (Cannabichromene)

CBC (Cannabichromene) Supports healthy inflammation response and promotes overall skin wellness.

CBG (Cannabigerol)

CBG (Cannabigerol) Promotes gut health, focus, and a calm nervous system.

CBN (Cannabinol)

CBN (Cannabinol) Encourages restful sleep and deep relaxation after active days.

Every Lillie & Lee CBD product is third-party tested for purity, potency, and safety - because your pet's wellness deserves nothing less than certainty. Download our Certificate of Analysis and see exactly what's inside.

Certificate of Analysis

Download COA

CBC (Cannabichromene)

CBC (Cannabichromene) Supports healthy inflammation response and promotes overall skin wellness.

CBG (Cannabigerol)

CBG (Cannabigerol) Promotes gut health, focus, and a calm nervous system.

CBN (Cannabinol)

CBN (Cannabinol) Encourages restful sleep and deep relaxation after active days.

See the Difference

Feature / Benefits
Lillie&Lee
Other Brands
Formula
Full spectrum, zero fillers, all natural
Isolate or broad spectrum with additives
Sourcing
Sourced & Made in the USA
Often imported hemp, overseas manufacturing
Testing
Third party tested, COA available
No testing or COA not publicly available
Ingredients
100% natural flavor, no artificial additives
Artificial flavors, synthetic carriers
Efficacy
Full entourage effect from full spectrum formula
Reduced efficacy from isolated CBD

Quality You Can Trust

At Lillie&Lee, quality and trust are at the heart of everything we do. From sourcing to packaging, each product is thoughtfully crafted with transparency, care, and your pet’s well-being in mind.

Ingredients You Know
Family You Can Trust
Made In The USA
No Artificial Additives

Rated by Real Pet Parents

4.8
Rated 4.8 out of 5 stars
Based on 596 reviews
95%would recommend these products
Slide 1 selected
Customers Talked About
596 reviews
  • Donita S.
    Verified Buyer
    Reviewing
    250mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age Under 1 yr
    Dog Size Small (under 25lbs)
    Primary Wellness Focus Calming
    Notice any changes Yes
    Easy to give Yes
    Rated 4 out of 5 stars
    3 minutes ago
    High anxiety dachshund

    The CBD oil for calm and comfort has really helped my high anxiety doxie Rudy. It has calmed his separation anxiety to where he doesn't howl and cry when he is with my dog sitter. Car rides are more relaxing, less panting by Rudy. He rests better and not as jumpy at new sounds. Will definitely keep my subscription.

    Period of useRated 0.0 on a scale of minus 2 to 2
  • Kathy L.
    Verified Buyer
    Reviewing
    1000mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 4 - 8 yrs
    Dog Size Small (under 25lbs)
    Primary Wellness Focus Calming, Digestion, Skin & Coat
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    3 hours ago
    Less arguments tween a frenchie & a pug

    We have a frenchie and a pug. The frenchie - he’s a bulldog- and all of life is ‘about him’ . If we pay more attention to the pug - the frenchie typically starts a fight.

    The frequency of ‘attention battles’ seems to be less now that they both get dosed w/1000 mg CBD 2X/day!!

    Thanks Lillie & Lee

    Period of useRated 2.0 on a scale of minus 2 to 2
  • Shiloh P.
    Verified Buyer
    Reviewing
    1000mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 9+ yrs
    Dog Size Extra large (91lbs+)
    Primary Wellness Focus Calming, Joint & Mobility
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    6 hours ago
    Great to have for the bad storms

    We use it to help our dogs with loud storms and fireworks. It is very helpful.

    Period of useRated 1.0 on a scale of minus 2 to 2
  • Brenda J.
    Verified Buyer
    Reviewing
    750mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 9+ yrs
    Dog Size Extra large (91lbs+)
    Primary Wellness Focus Joint & Mobility, Allergies, General Health, Aging Gracefully
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    6 hours ago
    Blessing

    We have a 10 1/2 old rotti who started taking this every 12 hours & she's starting to trott along on walks again. 😍

    Period of useRated 2.0 on a scale of minus 2 to 2
  • Carol H.
    Verified Buyer
    Reviewing
    1000mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 9+ yrs
    Dog Size Small (under 25lbs)
    Primary Wellness Focus Allergies, Calming, Joint & Mobility, General Health
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    7 hours ago
    Helping my senior dog rest

    Helps her rest more calmly

    She is 18 years old

    Period of useRated 0.0 on a scale of minus 2 to 2