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America’s Most Followed Pet Wellness Brand

4.8
Rated 4.8 out of 5 stars
785 Reviews

250mg CBD Oil | Calm + Comfort - for Pets

250mg CBD Oil | Calm + Comfort - for Pets

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ATTENTION: NEW CBD LAW RESTRICTIONS

250mg CBD Oil | Calm + Comfort - for Pets

If you are shipping to any of these states please purchase our organic CBD Isolate Oil here:

CA, GA, HI, KS, LA, SD, VA, & MS

Purchase CBD Isolate >
Quantity
  • 90 Day Money Back Guarantee
  • Free Shipping On Order $125+

CA Residents:

IMPORTANT: We are no longer able to ship full spectrum CBD to CALIFORNIA as of July 1st. (CA Law SB 378)

⚠️ WARNING: Cancer and Reproductive Harm – www.P65Warnings.ca.gov

Product Description

Our 250mg CBD Oil delivers a full‐spectrum botanically derived cannabidiol formula that promotes relaxation, supports joint comfort, and encourages restful sleep.

Ingredients

  • 100% Full Spectrum CBD Oil
  • MCT Oil (for optimal absorption)

Potency: 250mg per 1 oz bottle

Problem?

Is stress, restlessness, or occasional aches slowing your pet down?

What It Is

  • Full‐Spectrum CBD Extract: Advanced, botanical extraction containing CBD along with naturally occurring minor cannabinoids and terpenes.
  • Two-Ingredients: Formulated for pets, with only CBD and flavor‐neutral CT carrier oil to suit every palate.
  • Consistent Strength: Each drop contains a reliable, measured amount of CBD to ensure effortless, accurate administration.

Why It Works

  • Stress Support: CBD interacts with the body’s endocannabinoid receptors to help calm overactive stress responses.
  • Joint & Muscle Relief: Naturally soothes discomfort by modulating inflammatory pathways, aiding mobility and ease of movement.
  • Sleep & Recovery: Encourages deeper, more restorative sleep cycles by balancing neurotransmitters involved in rest regulation.
  • Holistic Balance: Supports overall endocannabinoid system health, enhancing emotional resilience and physical well-being across species.

How to Use

Our 250mg CBD is best for pets under 40lbs.

Administer orally 1-2 times daily. Can be given during or after mealtime. For optimal benefits, we recommend daily use. Dosage dependent on weight:

Recommended use:

Pets 1–24 lbs: 1/2 dropper (~4 mg)

Pets 25–50 lbs: Full dropper (~8 mg)

  • Premium Quality
  • No Junk Ever!
  • Pet-Parent Trusted
  • Community You Love
View full details

Why Dogs Loves It

Pure Ingredients, Zero Compromise.

No fillers, ever. Just full spectrum CBD in its most natural form — because your dog deserves nothing but the best.

Calm When It Counts

Fireworks, car rides, vet visits — life can be stressful for pups. Our CBD oil helps them stay cool, relaxed, and happy no matter what's happening around them.

Wake Up Wagging

Great days start with great sleep. Our CBD oil helps your pup get the deep, restorative rest they need to feel their absolute best.

Move More, Hurt Less

Our formula supports better mobility and healthier joints so they can keep up with the fun.

Tested. Verified. Transparent.

Meet the cannabinoids working for your pet.

Every Lillie & Lee CBD product is third-party tested for purity, potency, and safety - because your pet's wellness deserves nothing less than certainty. Download our Certificate of Analysis and see exactly what's inside.

Certificate of Analysis

Download COA

CBC (Cannabichromene)

CBC (Cannabichromene) Supports healthy inflammation response and promotes overall skin wellness.

CBG (Cannabigerol)

CBG (Cannabigerol) Promotes gut health, focus, and a calm nervous system.

CBN (Cannabinol)

CBN (Cannabinol) Encourages restful sleep and deep relaxation after active days.

Every Lillie & Lee CBD product is third-party tested for purity, potency, and safety - because your pet's wellness deserves nothing less than certainty. Download our Certificate of Analysis and see exactly what's inside.

Certificate of Analysis

Download COA

CBC (Cannabichromene)

CBC (Cannabichromene) Supports healthy inflammation response and promotes overall skin wellness.

CBG (Cannabigerol)

CBG (Cannabigerol) Promotes gut health, focus, and a calm nervous system.

CBN (Cannabinol)

CBN (Cannabinol) Encourages restful sleep and deep relaxation after active days.

See the Difference

Feature / Benefits
Lillie&Lee
Other Brands
Formula
Full spectrum, zero fillers, all natural
Isolate or broad spectrum with additives
Sourcing
Sourced & Made in the USA
Often imported hemp, overseas manufacturing
Testing
Third party tested, COA available
No testing or COA not publicly available
Ingredients
100% natural flavor, no artificial additives
Artificial flavors, synthetic carriers
Efficacy
Full entourage effect from full spectrum formula
Reduced efficacy from isolated CBD

Quality You Can Trust

At Lillie&Lee, quality and trust are at the heart of everything we do. From sourcing to packaging, each product is thoughtfully crafted with transparency, care, and your pet’s well-being in mind.

Ingredients You Know
Family You Can Trust
Made In The USA
No Artificial Additives

Rated by Real Pet Parents

4.8
Rated 4.8 out of 5 stars
Based on 785 reviews
95%would recommend these products
Slide 1 selected
Reviews Summary
Customers say these soft chews and CBD oil help their dogs feel calmer and more relaxed, particularly during stressful situations like storms and fireworks. Many report improved mobility and comfort in senior dogs with joint concerns. Common feedback includes reduced anxiety, better sleep, and increased playfulness. Some users note the products work best with consistent daily use. A few mention their dogs were picky about the taste or experienced minor digestive adjustments. Overall, customers appreciate the ease of administration and report noticeable improvements in their pets' comfort and behavior.
Customers Talked About
785 reviews
  • ELIZABETH G.
    Verified Buyer
    Reviewing
    CBD Soft Chews | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 1 - 3 yrs
    Dog Size Large (51lbs-90lbs
    Primary Wellness Focus Calming
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    1 month ago
    So far, so good...

    I have a 13 month old, deaf, hound/pitty mix. Frankie is super sweet and smart, but was clawing at the walls when I went to work causing a lot of damage. Later he even did it right in front of me. We started with the CBD Soft Chews a couple of weeks ago. I do one whole one in the AM and a half in the evening. The change has been beyond my expectaions!!! He is much calmer in a secure sort of way. I swear he actually looked at me the other day and I thought he was thinking how happy he was. Not kidding! Even my older dog likes him better now, and that is a big deal! Sadly since am using 1.5 chews a day I will run out before my 30-day reorder is due.

    Period of useRated -1.0 on a scale of minus 2 to 2
  • Sharon M.
    Verified Buyer
    Reviewing
    750mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 1 - 3 yrs
    Dog Size Small (under 25lbs)
    Primary Wellness Focus Calming, Allergies, Joint & Mobility, Skin & Coat, Digestion
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    1 month ago
    Game Changer

    I rescued Taco last November 2025 from a hoarding case from Texas. 10 dogs were brought back to a Washington Missouri rescue I have volunteered with for many years. They all had heartworms and scared. I ended up fostering to adopt Taco after losing my 15 year old dog suddenly. Taco was so scared of car rides, every loud noise and just kept shaking. I took him to Florida with me and had to use Trazadone to keep him calm. I didn't like the after effects it had. So I ordered the CBD. Just in 3 weeks I started working with him to get used to my car for Vet trips and just to different places to walk him where it was calm as he was recovering from heartworm treatment. He stopped hiding when I got his leash. He started going to the garage wagging his tail to get to my car. They didn't have to sedate him at the Vet's office. Then we had another trip to Florida in July and he was so happy. He was looking out the window. When I knew Thunderstorms were coming, I gave him a few drops and he didn't hide. He's become such a confident dog. The CBD has let me really work with his training to keep exposing him to new things.

    Period of useRated 2.0 on a scale of minus 2 to 2
  • kris d.
    Verified Buyer
    Reviewing
    250mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Primary Wellness Focus Calming
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    1 week ago
    good relief for my fur baby

    i looove this product and have been using it on my kitty's gingivitis for months. it has taken away a lot of her discomfort...and she loves it too!!! annabelle just opens her mouth every time and allows me to apply it on her gums without any fight! i only wish that cbd would heal gingivitis. great product!!!!

    Period of useRated 2.0 on a scale of minus 2 to 2
  • Wendy W.
    Verified Buyer
    Reviewing
    CBD Soft Chews | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 4 - 8 yrs
    Dog Size Medium (25lbs-50lbs)
    Primary Wellness Focus Calming
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    3 weeks ago
    These CBD chews are a lifesaver

    My rescue dog has nightmares and the first thing she does is attack whoever is closest. My husband, myself and my other rescue dog have been bitten several times. We tried at least 10 different products but nothing worked until we tried these chews. Now she mostly sleeps through the night. When she does have an occasional bad dream, she's not as aggressive and usually falls right back to sleep. These chews are currently out of stock and we hope they get replenished soon before we all start suffering again.

    Period of useRated 2.0 on a scale of minus 2 to 2
  • Terri H.
    Verified Buyer
    Reviewing
    750mg CBD Oil | Calm + Comfort - for Pets
    I recommend this product
    Dog Age 9+ yrs
    Dog Size Large (51lbs-90lbs
    Primary Wellness Focus Calming, General Health, Joint & Mobility, Aging Gracefully, Skin & Coat
    Notice any changes Yes
    Easy to give Yes
    Rated 5 out of 5 stars
    1 month ago
    Better for Bailey

    This is our beautiful rescue Bailey we have had her for 5 years she is now 10 and she has such a fear of fireworks or anything that sounds like fireworks and we started her on CBD a couple weeks before July 4th and what a difference it has made in her anxiety and I noticed so many other things that have improved with her. She has more energy she’s walking better just an all around change in her in general. Thank you Lee for this wonderful product and thank you for all you do! My dream is to visit your sanctuary you are such an inspiration to so many people and we truly believe in Adopt don’t shop 🐕‍🦺🐾🥰Thank you for everything you do….Terri and Joel Hammer and Bailey Hammer🐾

    Period of useRated 2.0 on a scale of minus 2 to 2